function [waveVamp, waveVlat, varargout] = roenne2012(stim,fsstim,stim_level,varargin)
%ROENNE2012 Simulate auditory brainstem responses (ABRs)
% Usage: [waveVamp, waveVlat] = roenne2012(stim,fsstim,stim_level)
%
% Input parameters:
% stim : stimuli
% fsstim : sampling frequency
% stim_level : level
%
% Output parameters:
% waveVamp : Amplitude of simulated ABR wave V.
% waveVlat : Latency of simulated ABR wave V peak.
%
%
% ROENNE2012(stim,fsstim,stim_level) returns simulated ABR wave V
% latency and amplitude. The stimulus stim must be defined in pascals
% and calibrated so a pure tone stimulus has an RMS value of 1. Transient
% stimuli (which this model is designed to simulate) has to be calibrated
% in peSPL acoustically. This is *not* the same as "just" having a
% numerical peak to peak value of the same level as the pure tone. For
% calibrated click, chirps and tone bursts, see ROENNE2012_CLICK,
% ROENNE2012_TONEBURSTS and ROENNE2012_CHIRP.
%
% The parameter fsstim gives the sampling frequency of the input
% stimulus, and stim_level the level. As input is calibrated to an
% RMS-value of 1, a stimulus level in (pe)SPL has to be set.
%
% Flags:
%
% 'plot' : Plot the output. See PLOT_ROENNE2012.
%
% 'no_plot' : Do not plot. This is the default.
%
% 'fsmod',fsmod : Auditory nerve model sampling frequency.
% Default value is 200000.
%
% 'flow',flow : Auditory nerve model lowest center frequency.
% Default value is 100 Hz.
%
% 'fhigh',fhigh : Auditory nerve model highest center frequency.
% Default value is 16000 Hz.
%
% 'min_modellength',mn : Minimum length of modelling measured in ms.
% Default value is 40.
%
% Please cite Rønne et al. (2012) and Zilany and Bruce (2007) if you use
% this model.
%
% See also: data_roenne2012 plot_roenne2012 plot_roenne2012_chirp
% plot_roenne2012_tonebursts demo_roenne2012 roenne2012_click
% roenne2012_chirp roenne2012_tonebursts exp_roenne2012 zilany2014
%
% References:
% C. Elberling, J. Calloe, and M. Don. Evaluating auditory brainstem
% responses to different chirp stimuli at three levels of stimulation.
% The Journal of the Acoustical Society of America, 128(1):215--223,
% 2010.
%
% F. M. Rønne, T. Dau, J. Harte, and C. Elberling. Modeling auditory
% evoked brainstem responses to transient stimuli. The Journal of the
% Acoustical Society of America, 131(5):3903--3913, 2012.
%
% M. S. A. Zilany and I. C. Bruce. Representation of the vowel (epsilon)
% in normal and impaired auditory nerve fibers: Model predictions of
% responses in cats. The Journal of the Acoustical Society of America,
% 122(1):402--417, jul 2007.
%
%
% Url: http://amtoolbox.org/amt-1.6.0/doc/models/roenne2012.php
% #StatusDoc: Perfect
% #StatusCode: Perfect
% #Verification: Verified
% #Requirements: M-Signal
% #Author: Peter L. Sondergaard (2012)
% This file is licensed unter the GNU General Public License (GPL) either
% version 3 of the license, or any later version as published by the Free Software
% Foundation. Details of the GPLv3 can be found in the AMT directory "licences" and
% at <https://www.gnu.org/licenses/gpl-3.0.html>.
% You can redistribute this file and/or modify it under the terms of the GPLv3.
% This file is distributed without any warranty; without even the implied warranty
% of merchantability or fitness for a particular purpose.
% Define input flags
definput.flags.plot = {'no_plot', 'plot'};
definput.keyvals.fsmod=200000;
definput.keyvals.flow = 100;
definput.keyvals.fhigh = 16000;
definput.keyvals.min_modellength=40;
[flags,kv] = ltfatarghelper({},definput,varargin);
%% Init
[ur,fs] = data_roenne2012;
% Assure minimum model length of 40ms
if length(stim)/fsstim < kv.min_modellength/1000
stim_temp = zeros(1, fsstim*kv.min_modellength/1000);
stim_temp(1:length(stim)) = stim;
stim = stim_temp;
end
%% ABR model
% call AN model, note that lots of extra outputs are possible
[ANout,vFreq] = zilany2007(stim_level, stim, fsstim, kv.fsmod, 'flow',kv.flow, 'fhigh',kv.fhigh);
% subtract 50 due to spontaneous rate
ANout = ANout-50;
% Sum in time across fibers, summed activity pattern
ANsum1 = sum(ANout,2);
% Downsample ANsum to get fs = fs_UR = 32kHz
ANsum = resample(ANsum1,fs,kv.fsmod);
% Simulated potential = UR * ANsum (* = convolution)
simpot = filter(ur,1,ANsum);
% Find max peak value (wave V)
maxpeak = max(simpot);
% Find corresponding time of max peak value (latency of wave V). The unit
% is [ms].
waveVlat = find(simpot == maxpeak)/fs*1000;
% find minimum in the interval from "max peak" to 6.7 ms later
minpeak = min(simpot(find(simpot == max(simpot)):...
find(simpot == max(simpot))+200));
% Calculate wave V amplitude, as the difference between the peak and the
% dip, in [\mu p] (micro pascals).
waveVamp = (maxpeak-minpeak);
if nargout >= 3
varargout{1} = simpot;
if nargout >= 4
varargout{2} = ANout;
end
end
end